Knowledge management support for enterprise distributed systems

Explosion of information and increasing demands on semantic processing web applications have software systems to their limits. To address the problem we propose a semantic based formal framework (ADP) that makes use of promising technologies to enable knowledge generation and retrieval. We argue that this approach is cost effective, as it reuses and builds on existing knowledge and structure. It is also a good starting point for creating an organisational memory and providing knowledge management functions

Enterprise engineering using semantic technologies

Modern Enterprises are facing unprecedented challenges in every aspect of their businesses: from marketing research, invention of products, prototyping, production, sales to billing. Innovation is the key to enhancing enterprise performances and knowledge is the main driving force in creating innovation. The identification and effective management of valuable knowledge, however, remains an illusive topic. Knowledge management (KM) techniques, such as enterprise process modelling, have long been recognised for their value and practiced as part of normal business. There are plentiful of KM techniques. However, what is still lacking is a holistic KM approach that enables one to fully connect KM efforts with existing business knowledge and practices already in IT systems, such as organisational memories. To address this problem, we present an integrated three-dimensional KM approach that supports innovative semantics technologies. Its automated formal methods allow us to tap into modern business practices and capitalise on existing knowledge. It closes the knowledge management cycle with user feedback loops. Since we are making use of reliable existing knowledge and methods, new knowledge can be extracted with less effort comparing with another method where new information has to be created from scratch

Can Taxes on Calorically Sweetened Beverages Reduce Obesity?

Beverage tax, obesity, overweight, Food Consumption/Nutrition/Food Safety, D12, H2, I18,

TROM: A Testing-based Method for Finding Transcriptomic Similarity of Biological Samples

Comparative transcriptomics has gained increasing popularity in genomic research thanks to the development of high-throughput technologies including microarray and next-generation RNA sequencing that have generated numerous transcriptomic data. An important question is to understand the conservation and differentiation of biological processes in different species. We propose a testing-based method TROM (Transcriptome Overlap Measure) for comparing transcriptomes within or between different species, and provide a different perspective to interpret transcriptomic similarity in contrast to traditional correlation analyses. Specifically, the TROM method focuses on identifying associated genes that capture molecular characteristics of biological samples, and subsequently comparing the biological samples by testing the overlap of their associated genes. We use simulation and real data studies to demonstrate that TROM is more powerful in identifying similar transcriptomes and more robust to stochastic gene expression noise than Pearson and Spearman correlations. We apply TROM to compare the developmental stages of six Drosophila species, C. elegans, S. purpuratus, D. rerio and mouse liver, and find interesting correspondence patterns that imply conserved gene expression programs in the development of these species. The TROM method is available as an R package on CRAN (http://cran.r-project.org/) with manuals and source codes available at http://www.stat.ucla.edu/ jingyi.li/software-and-data/trom.html

Building fault detection data to aid diagnostic algorithm creation and performance testing.

It is estimated that approximately 4-5% of national energy consumption can be saved through corrections to existing commercial building controls infrastructure and resulting improvements to efficiency. Correspondingly, automated fault detection and diagnostics (FDD) algorithms are designed to identify the presence of operational faults and their root causes. A diversity of techniques is used for FDD spanning physical models, black box, and rule-based approaches. A persistent challenge has been the lack of common datasets and test methods to benchmark their performance accuracy. This article presents a first of its kind public dataset with ground-truth data on the presence and absence of building faults. This dataset spans a range of seasons and operational conditions and encompasses multiple building system types. It contains information on fault severity, as well as data points reflective of the measurements in building control systems that FDD algorithms typically have access to. The data were created using simulation models as well as experimental test facilities, and will be expanded over time